Browsing by Author "Bakir, Sevtap"
Now showing items 1-17 of 17
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Antioxidant-oxidant status in patients with hydatid cyst
Bakir, Sevtap; Celiksoz, Ali; Celik, V. Kenan; Sari, Ismail; Aydin, Huseyin (WALTER DE GRUYTER GMBH, 2012)Objectives: To determine whether oxidative stress plays a role in the pathogenesis of hydatid cyst by examining levels of total antioxidant status, total oxidant status, oxidative stress index, and activities of the enzymes ... -
The Association of Plasminogen Activator Inhibitor Type 1 (PAI-1) Level and PAI-1 4G/5G Gene Polymorphism with the Formation and the Grade of Endometrial Cancer
Yildirim, Malik Ejder; Karakus, Savas; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Ersan, Serpil; Bakir, Sevtap (SPRINGER/PLENUM PUBLISHERS, 2017)Plasminogen activator inhibitor type 1 (PAI-1) is a serine protease inhibitor (Serpine 1), and it inhibits both tissue plasminogen activator and urokinase plasminogen activator which are important in fibrinolysis. We aimed ... -
Comparison of Oxidant/Antioxidant, Detoxification Systems in Various Tissue Homogenates and Mitochondria of Rats with Diabetes Induced by Streptozocin
Celik, Veysel Kenan; Sahin, Zeynep Deniz; Sari, Ismail; Bakir, Sevtap (HINDAWI PUBLISHING CORPORATION, 2012)Objective. Oxidative stress is considered to be the main factor in the development of diabetic complications and tissue injury. our objective was to investigate and compare the oxidant/antioxidant conditions and detoxification ... -
Comparison of sulfur transferases in various tissue and mitochondria of rats with type 1 diabetes mellitus induced by streptozotocin
Aydin, Huseyin; Celik, Veysel Kenan; Sari, Ismail; Tekin, Yusuf Kenan; Demirpence, Ozlem; Bakir, Sevtap (SPRINGER INDIA, 2016)This study aims to investigate the relationship between sulfurtransferase (STS) activities [rhodanese (TST), mercaptopyruvate sulfurtransferase (MST)] involved in the catalysis of several biochemical reactions including ... -
DETERMINATION OF SERUM ADENOSINE DEAMINASE AND XANTHINE OXIDASE LEVELS IN PATIENTS WITH CRIMEAN-CONGO HEMORRHAGIC FEVER
Celik, V. Kenan; Sari, Ismail; Engin, Aynur; Yildiz, Guersel; Aydin, Hueseyin; Bakir, Sevtap (HOSPITAL CLINICAS, UNIV SAO PAULO, 2010)OBJECTIVE: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo ... -
Effects of cement dust exposure on malonyldialdehyde levels and catalaze activities in red blood cells
Nur, Naim; Yilmaz, Abduelkerim; Ersan, Serpil; Gueler, Nuran; Suemer, Haldun; Bakir, Sevtap (ASIAN JOURNAL OF CHEMISTRY, 2008)This study was designed to investigate the plasma oxidant and antioxidant status in both cement plant workers and control subjects. Malonyldialdehyde (MDA) levels and catalaze (CAT) activity were investigated for 42 cement ... -
Erythrocyte Sedimentation Rate, Serum Amyloid A and C-reactive Protein Levels in Patients with Acute Brucellosis
Celik, V. Kenan; Sari, Ismail; Bakir, Sevtap; Engin, Aynur; Bakir, Deniz; Sari, Musa; Poyraz, Omer; Yildiz, Gursel (PROFESSIONAL MEDICAL PUBLICATIONS, 2011)Objective: To determine the levels of and the relationship between serum amyloid A (SAA), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in patients with acute brucellosis. Methodology: SAA, CRP and ESR ... -
Evaluation of the associations between endothelial dysfunction, inflammation and coagulation in Crimean-Congo hemorrhagic fever patients
Dogan, Halef Okan; Buyuktuna, Seyit Ali; Kapancik, Sercan; Bakir, Sevtap (SPRINGER WIEN, 2018)Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic viral disease. The aim of this study was to evaluate the association between inflammation, coagulation and endothelial dysfunction in CCHF. The study population ... -
Evaluation of the relationship between serum levels of VEGF and sVEGFR1 with mortality and prognosis in patients with Crimean-Congo hemorrhagic fever
Bakir, Mehmet; Bakir, Sevtap; Sari, Ismail; Celik, Veysel Kenan; Gozel, Mustafa Gokhan; Engin, Aynur (WILEY-BLACKWELL, 2013)The most accepted view to explaining the pathogenesis of Crimean-Congo hemorrhagic fever (CCHF) is endothelial damage. This study was conducted in a University hospital to investigate the serum levels and prognostic ... -
Examination of free radical metabolism and antioxidant defence system elements in patients with obsessive-compulsive disorder
Ersan, Serpil; Bakir, Sevtap; Ersan, E. Erdal; Dogan, Orhan (PERGAMON-ELSEVIER SCIENCE LTD, 2006)Free radicals and oxidative stress are involved in the pathogenesis of various diseases. Malondialdehyde (MDA) is a natural product of lipid peroxidation in all mammalian cells. Vitamins C and E are nonenzymatic antioxidant ... -
Increased Irisin Concentrations in Patients with Crimean-Congo Hemorrhagic Fever
Buyuktuna, Seyit Ali; Dogan, Halef Okan; Bakir, Deniz; Ersan, Serpil; Koc, Derya; Bakir, Sevtap (NATL INST INFECTIOUS DISEASES, 2017)Crimean -Congo Hemorrhagic Fever (CCHF) is a life-threatening viral infection. The pathogenesis of the disease is not well understood. The aim of this study was to determine the change in irisin concentrations in patients ... -
Malondialdehyde, vitamin E, and anti-oxidant enzyme activity levels in patients with crimean-congo hemorrhagic fever
Aydin, Huseyin; Yildiz, Gursel; Engin, Aynur; Yilmaz, Abdulkerim; Celik, Kenan; Bakir, Sevtap (ACADEMIC JOURNALS, 2010)Crimean-congo hemorrhagic fever (CCHF) is a viral disease that can be seen in people epidemically or as single patient. CCHF is a highly deadly disease caused by Nairovirus from Bunyaviridae family. Endothelial damage ... -
Relationship of plasma cell-free DNA level with mortality and prognosis in patients with Crimean-Congo hemorrhagic fever
Bakir, Mehmet; Engin, Aynur; Kuskucu, Mert Ahmet; Bakir, Sevtap; Gundag, Omur; Midilli, Kenan (WILEY, 2016)Crimean-Congo hemorrhagic fever (CCHF) is a viral infection. Circulating plasma cell-free DNA (pcf-DNA) is a novel marker indicating cellular damage. So far, the role of pcf-DNA did not investigate in CCHF patients. In the ... -
Role of MTHFR gene polymorphisms, serum tissue inhibitor of metalloproteinases-1, thymus chemokine-1 and thrombospondin-1 in endometrial cancer
Yildirim, Malik Ejder; Kilicgun, Hasan; Kurtulgan, Hande Kucuk; Karakus, Savas; Ersan, Serpil; Bakir, Sevtap; Sezgin, Ilhan (E-CENTURY PUBLISHING CORP, 2016)The aim of this study was to evaluate the relationship between the MTHFR gene variants (677 C -> T and 1298 A -> C), serum tissue metalloproteinases inhibitor (TIMP-1), thrombospondin-1 (TSP-1), thymus chemokine-1 (TCK-1) ... -
Some acute phase reactants and cholesterol levels in serum of patient with Crimean-Congo haemorrhagic fever
Sari, Ismail; Bakir, Sevtap; Engin, Aynur; Aydin, Huseyin; Poyraz, Omer (ASSOC BASIC MEDICAL SCI FEDERATION BOSNIA & HERZEGOVINA SARAJEVO, 2013)The purpose of this study is to determine erythrocyte sedimentation rate (ESR), C - reactive protein (CRP), serum amyloid-A (SAA) and cholesterol levels in patients with Crimean-Congo Hemorrhagic Fever (CCHF) and determine ... -
Thiol Disulfide Homeostasis in Schizophrenic Patients Using Atypical Antipsychotic Drugs
Dogan, Halef Okan; Ersan, Etem Erdal; Aydin, Huseyin; Erdogan, Serpil; Ersan, Serpil; Alisik, Murat; Bakir, Sevtap; Erel, Ozcan; Koc, Derya (KOREAN COLL NEUROPSYCHOPHARMACOLOGY, 2018)Objective: Schizophrenia is a severe, debilitating mental disorder characterized by behavioral abnormalities. Although several studies have investigated the role of oxidative stress and the effects of antipsychotic drugs ... -
Xanthine oxidase, adenosine deaminase and vitamin E levels in patients with schizophrenia
Kilicgun, Hasan; Ersan, Etem Erdal; Bakir, Sevtap; Ersan, Serpil; Koc, Derya; Demirpence, Ozlem; Dogan, Kubra (CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2016)Objective: Neuronal damage caused by free radicals is believed to be effective in pathogenesis of several psychiatric disorders. This belief is due to the toxic effects of free radicals that play a role in oxidative stress. ...